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VOLUME 14 , ISSUE 1 ( January-March, 2024 ) > List of Articles

REVIEW ARTICLE

Comparison of In-office Bleaching Agent Application Times on Tooth Sensitivity and Color Change: A Systematic Review and Meta-analysis

Yasmeen M Azeem, Kiranmayi Govula, Lavanya Anumula, Harika Paluru, Chandrasekhar Soudagiri

Keywords : Bleaching times, Color change, Hydrogen peroxide, In-office tooth bleaching, Tooth sensitivity

Citation Information : Azeem YM, Govula K, Anumula L, Paluru H, Soudagiri C. Comparison of In-office Bleaching Agent Application Times on Tooth Sensitivity and Color Change: A Systematic Review and Meta-analysis. Int J Prosthodont Restor Dent 2024; 14 (1):50-57.

DOI: 10.5005/jp-journals-10019-1439

License: CC BY-NC 4.0

Published Online: 30-03-2024

Copyright Statement:  Copyright © 2024; The Author(s).


Abstract

Purpose: To compare the effect of in-office bleaching agent application times on tooth sensitivity and degree of color change. Materials and methods: PubMed, Web of Science, EBSCO, Scopus, Cochrane Library, DOAJ, LILAC, gray literature, and manual search. Randomized clinical trials or clinical studies that recruited patients aged 18 years or above for in-office tooth bleaching were included. The focused question was, “Do application times of in-office bleaching agents affect tooth sensitivity and degree of color change”? The risk of bias (RoBs) and meta-analysis were analyzed using review-manager software. Results: The database search identified 159 citations and 13 citations through manual search. After removing duplicates, the abstracts of 93 studies were assessed. Around 10 full-text articles were studied, and finally, four articles were included for qualitative analysis. The RoBs in the four included studies was considered to be low. Conclusion: Systematic review and meta-analyses showed that single prolonged bleaching has significantly reduced postbleaching tooth sensitivity compared to the multiple application times of the bleaching agent. The color change seemed the same with both application times of the bleaching agent.


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  1. Joiner A. Tooth color: a review of the literature. J Dent 2004;32(Supplement 1):3–12. DOI: 10.1016/j.jdent.2003.10.013
  2. Tin-Oo MM, Saddki N, Hassan N. Factors influencing patient satisfaction with dental appearance and treatments they desire to improve aesthetics. BMC Oral Health 2011;11:6. DOI: 10.1186/1472-6831-11-6
  3. Barghi N. Making a clinical decision for vital tooth bleaching: at-home or in-office?. Compend Contin Educ Dent 1998;19(8):831–838. PMID: 9918107.
  4. Blankenau R, Goldstein RE, Haywood VB. The current status of vital tooth whitening techniques. Compend Contin Educ Dent 1999;20(8):781–788. PMID: 10649952.
  5. Basting RT, Amaral FL, Franca FM, et al. Clinical comparative study of the effectiveness of and tooth sensitivity to 10% and 20% carbamide peroxide home–use and 35% and 38% hydrogen peroxide in-office bleaching materials containing desensitizing agents. Oper Dent 2012;37(5):464–473. DOI: 10.2341/11-337-C
  6. Nathanson D. Vital tooth bleaching: sensitivity and pulpal considerations. J Am Dent Assoc 1997;128(Supplement 4):41S–44S. DOI: 10.14219/jada.archive.1997.0423
  7. Costa CA, Riehl H, Kina JF, et al. Human pulp responses to in-office tooth bleaching. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2010;109(4):e59–e64. DOI: 10.1016/j.tripleo.2009.12.002
  8. Reis A, Tay LY, Herrera DR, et al. Clinical effects of prolonged application time of an in-office bleaching gel. Oper Dent 2011;36(6):590–596. DOI: 10.2341/10-173-C
  9. Al-Qunaian TA, Matis BA, Cochran MA. In vivo kinetics of bleaching gel with three-percent hydrogen peroxide within the first hour. Oper Dent 2003;28(3):236–241. PMID: 12760694.
  10. Perdigão J, Baratieri LN, Arcari GM. Contemporary trends and techniques in tooth whitening: a review. Pract Proced Aesthet Dent 2004;16(3):185–192. PMID: 15199693.
  11. He LB, Shao MY, Tan K, et al. The effects of light on bleaching and tooth sensitivity during in-office vital bleaching: a systematic review and meta-analysis. J Dent 2012;40(8):644–653. DOI: 10.1016/j.jdent.2012.04.010
  12. Price RB, Sedarous M, Hiltz GS. The pH of tooth whitening products. J Canad Dent Assoc 2000;66(8):421–426. PMID: 11040525.
  13. Soares DG, Ribeiro AP, da Silveira Vargas F, et al. Efficacy and cytotoxicity of a bleaching gel after short application times on dental enamel. Clin Oral Investig 2013;17(8):1901–1909. DOI: 10.1007/s00784-012-0883-1
  14. Soares DG, Basso FG, Hebling J, et al. Concentrations of and application protocols for hydrogen peroxide bleaching gels: effects on pulp cell viability and whitening efficacy. J Dent 2014;42(2):185–198. DOI: 10.1016/j.jdent.2013.10.021
  15. Soares DG, Basso FG, Pontes EC, et al. Effective tooth-bleaching protocols capable of reducing H(2)O(2) diffusion through enamel and dentine. J Dent 2014;42(3):351–358. DOI: 10.1016/j.jdent.2013.09.001
  16. Cintra LT, Benetti F, da Silva Facundo AC, et al. The number of bleaching sessions influences pulp tissue damage in rat teeth. J Endod 2013;39(12):1576–1580. DOI: 10.1016/j.joen.2013.08.007
  17. Martins IE, Onofre S, Franco N, et al. Effectiveness of in-office hydrogen peroxide with two different protocols: a two-center randomized clinical trial. Oper Dent 2018;43(4):353–361. DOI: 10.2341/17-128-C
  18. Kose C, Calixto AL, Bauer JR, et al. Comparison of the effects of in-office bleaching times on whitening and tooth sensitivity: a single-blind, randomized clinical trial. Oper Dent 2016;41(2):138–145. DOI: 10.2341/15-085-C
  19. Marson FC, Sensi LG, Vieira LCC, et al. Clinical evaluation of in-office dental bleaching treatments with and without the use of light-activation sources. Oper Dent 2008; 33(1):15–22. DOI: 10.2341/07-57
  20. Madhuri BV. Comparison of the effects of in-office bleaching times on whitening and tooth sensitivity: an in vivo study. (Doctoral dissertation, Ragas Dental College and Hospital, Chennai).
  21. Da Silva KL, Favoreto MW, Centenaro GG, et al. Can all highly concentrated in-office bleaching gels be used as a single application? Clin Oral Investig 2023;27(7):3663–3671. DOI: 10.1007/s00784-023-04980-w
  22. Ozdemir ZM, Surmelioglu D. Effects of different bleaching application time on tooth color and mineral alteration. Ann Anat 2021;233:151590. DOI: 10.1016/j.aanat.2020.151590
  23. Borges AB, de Abreu FS, Mailart MC, et al. Efficacy and safety of bleaching gels according to the application protocol. Oper Dent 2021;46(2):E105–E116. DOI: 10.2341/19-253-L
  24. Meireles SS, Santos ME, Lustosa ÍM, et al. Effects of a reduced in-office bleaching protocol with 37.5% hydrogen peroxide on effectiveness and tooth sensitivity: a double-blind randomized clinical trial. J Esthet Restor Dent 2021;33(5):824–831. DOI: 10.1111/jerd.12744
  25. Favoreto MW, Cordeiro DC, Centenaro GG, et al. Evaluating color change and hydrogen peroxide penetration in human and bovine teeth through in-office bleaching procedures. J Esthet Restor Dent 2024. DOI: 10.1111/jerd.13207
  26. Acuña ED, Parreiras SO, Favoreto MW, et al. In-office bleaching with a commercial 40% hydrogen peroxide gel modified to have different pHs: color change, surface morphology, and penetration of hydrogen peroxide into the pulp chamber. J Esthet Restor Dent 2022;34(2):322–327. DOI: 10.1111/jerd.12453
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