This case report describes an innovative approach to creating a smile makeover using a fully digital workflow. An intraoral scan was integrated into the patient's frontal smile using digital software to create a three-dimensional (3D) digital smile design and virtual mock-up, guided by universal esthetic analysis principles. The virtual mock-up was 3D printed to fabricate an index for the clinical mock-up. The clinical mock-up was applied using acrylic materials to translate the virtual mock-up clinically and obtain patient consent. Esthetic analyses were performed to obtain optimum esthetic, functional, and occlusal stabilities. Guided to veneer preparations were performed. Retraction cords were placed, and an intraoral scan was performed for the #15 and #25 veneers. The margin was defined digitally, and the stereolithography (STL) files were then transferred digitally to the laboratory technician for veneer fabrication. Provisional veneers were cemented using the spot-etch technique. Computer-aided design and computer-aided manufacturing (CAD/CAM) lithium disilicate veneers were bonded to the prepared teeth. Esthetic function and occlusion remained stable at the 1-year follow-up visit. The use of digital workflow in managing esthetic cases enhanced the treatment predictability and increased the survival and success of the restorations due to the conservation of tooth structure.