Purpose: The purpose of this article was to evaluate and analyze the stress distribution in multiple single-piece dental implants before and after syncrystallization using finite element models. Materials and methods: Two maxillary three-dimensional (3D) finite element models were constructed using Creo elements software, with each model consisting of eight single-piece implants. Implants were positioned in the central incisor, canine, second premolar, and second molar regions, respectively, in both quadrants. In model A, no syncrystallization was done, and in model B, syncrystallization was done. Acrylic provisional restoration was constructed using 3D over the implants in both models A and B. Axial loading forces of 300 N in the anterior region (incisor to canine) and 800 N in the posterior region (premolar to molar) were applied using analysis of systems (ANSYS) software to analyze and compare the stress distribution between two finite element models. Results: Model B with syncrystallization showed less stress at implant, hard bone, and soft bone levels when compared to model A. A significant stress reduction of about 23% at the implant level, 47% at the hard bone level, and 42% at the soft bone level was seen. When compared at the provisional acrylic level, model B showed reduced stress compared to model A. Conclusion: Immediate loading after syncrystallization of multiple single-piece dental implants to titanium bars of sufficient thickness showed uniform and reduced stress distribution and aids in osseointegration when compared to conventional immediate loading of multiple single-piece dental implants.