Aim: To study the effect of various surface conditioning methods on shear bond strength of resin luting cement to all ceramic (zirconia) coping materials. Materials and methods: Thirty-two caries-free human mandibular 3rd molars were embedded in acrylic blocks and 32 zirconia blocks of 5 x 5 x 5 mm dimension fabricated. Amongst them eight zirconia blocks were used without any surface treatment, eight were etched with 9% hydrofluoric acid, 8 were air abraded with 150 microns alumina sand particles, with rest eight both acid etching and air abrasion surface treatments were done. All zirconia blocks were luted with dual-cure resin cement to conditioned dentin surface of acrylic embedded mandibular 3rd molars. Shear bond strength of resin cement was evaluated with the help of instron universal testing machine. Results: The mean shear bond strength of cemented air-abraded zirconia ceramics to dentine with dual-cure resin cement (ivoclair) exhibited the highest bond strength of 19.44 MPa with a standard error of 1.13. The mean shear bond strength of zirconia ceramics with acid etched plus air abrasion surface treatment luted to dentine with dual-cure resin cement (ivoclair) exhibited bond strength of 13.20 MPa with a standard error of 0.78. The mean shear bond strength of zirconia ceramics with acid etched surface treatment, luted to dentine with dual-cure resin cement (ivoclair) exhibited bond strength of 10.91 MPa with a standard error of 0.57. The mean shear bond strength of zirconia ceramics without any surface treatment luted to dentine with dual-cure resin cement (ivoclair) exhibited bond strength of 10.49 MPa with a standard error of 0.56. Conclusion: Zirconia blocks with air abrasion shows the highest shear strength followed by acid etched plus air abrasion followed by only acid etching with 9% hydrofluoric acid.