Denture stomatitis is a relatively common oral mycotic infection occurring in partial or complete denture wearers. Candida albicans is one of the principal etiological factors, with number of local or systemic co-factors influencing the occurrence. While an array of agents are involved in the occurrence and progression of the lesion, one could not expect monotony in the treatment modality. Spectrum of treatment modes have been practised to manage denture stomatitis, which include proper maintenance of oral and denture hygiene to systemic antifungal medication. Here we present a case of denture stomatitis, successfully treated with diode laser with 6 months follow-up.